HOMA-IR calculator — a cautious tool
HOMA-IR (Homeostasis Model Assessment of Insulin Resistance) is a score calculated from fasting glucose and fasting insulin. It is used clinically to guide investigation of insulin resistance in the context of PCOS / PMOS.
Its limitations are important to understand: threshold values vary between countries, laboratories, and insulin assay methods. A score is not read in isolation — it must be interpreted with your doctor, in the context of your full clinical picture. Learn more about insulin resistance in PCOS.
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Conversion: 1 g/L ≈ 5.55 mmol/L ≈ 100 mg/dL
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Formula used (source: Matthews DR et al., 1985, referenced in international guidelines):
- In mg/dL: HOMA-IR = (glucose mg/dL × insulin µU/mL) / 405
- In mmol/L: HOMA-IR = (glucose mmol/L × insulin µU/mL) / 22.5
Related resources: Insulin resistance and PCOS · PCOS lab tests guide · Prepare my appointment