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Tool · updated 16 May 2026

HOMA-IR calculator — a cautious tool

HOMA-IR (Homeostasis Model Assessment of Insulin Resistance) is a score calculated from fasting glucose and fasting insulin. It is used clinically to guide investigation of insulin resistance in the context of PCOS / PMOS.

Its limitations are important to understand: threshold values vary between countries, laboratories, and insulin assay methods. A score is not read in isolation — it must be interpreted with your doctor, in the context of your full clinical picture. Learn more about insulin resistance in PCOS.

This tool calculates a score — it does not diagnose anything. HOMA-IR is one indicator among many. Its thresholds vary by laboratory and clinical context. Discuss your result with your doctor — do not make any treatment decision based on this calculation alone.
This tool does not diagnose insulin resistance. Thresholds vary by laboratory, assay method, country, and clinical context. Always discuss your result with your healthcare provider.
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Conversion: 1 g/L ≈ 5.55 mmol/L ≈ 100 mg/dL

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Formula used (source: Matthews DR et al., 1985, referenced in international guidelines):

  • In mg/dL: HOMA-IR = (glucose mg/dL × insulin µU/mL) / 405
  • In mmol/L: HOMA-IR = (glucose mmol/L × insulin µU/mL) / 22.5

Related resources: Insulin resistance and PCOS · PCOS lab tests guide · Prepare my appointment